Recombinant Proteins

Active Protein Kinases / Recombinant Protein Kinases

Field of Application

Recombinant protein kinases can be used for the identification and characterization of kinase inhibitors. Protein kinases phosphorylate Serine or Threonine aminoacids on substrates to modulate a variety of cellular signaling processes.

ProQinase offers a large panel of active recombinant protein kinases. Our active kinase enzymes can be purchased as aliquots off the shelf and are available in bulk quantities.

Active recombinant protein kinases and recombinant proteins of other targets can be produced custom-tailored according to the needs of your drug discovery project.

All of our active enzymes are tested for activity in radiometric kinase activity assays to ensure the high quality of our products. Lot specific activity information is available to ensure reproducible results of your screening project.

 

Our Products

Product Product Number ADP-Glo™ Data Sheet Product Description Synonyms
ProQinase™ ABL1 0992-0000-1
Yes
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human, internal fragment, GST-HIS fusion protein, expressed in Sf9 cells

ABL1, ABL, JTK7, p150, c-ABL, v-abl, ABL1 wt
ProQinase™ ABL1 E255K 0924-0000-1
Yes
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human, internal fragment, E255K mutation, GST-HIS fusion protein, expressed in Sf9 cells

ABL1, c-Abl, JTK7, p150
ProQinase™ ABL1 F317I 0989-0000-1
Yes
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human, internal fragment, F317I mutation, GST-HIS fusion protein, expressed in Sf9 cells

ABL1, ABL, JTK7, p150, c-ABL, v-abl
ProQinase™ ABL1 G250E 0925-0000-1
Yes
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human, internal fragment, G250E mutation, GST-HIS fusion protein, expressed in Sf9 cells

ABL1, ABL, JTK7, p150, c-ABL, v-abl
ProQinase™ ABL1 H396P 0991-0000-1
Yes
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human, internal fragment, H396P mutation, GST-HIS fusion protein, expressed in Sf9 cells

ABL1, ABL, JTK7, p150, c-ABL, v-abl
ProQinase™ ABL1 M351T 0990-0000-1
Yes
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human, internal fragment, M351T mutation, GST-HIS fusion protein, expressed in Sf9 cells

ABL1, ABL, JTK7, p150, c-ABL, v-abl
ProQinase™ ABL1 Q252H 0926-0000-1
Yes
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human, internal fragment, Q252H mutation, GST-HIS fusion protein, expressed in Sf9 cells

ABL1, ABL, JTK7, p150, c-ABL, v-abl
ProQinase™ ABL1 T315I 0757-0000-1
Yes
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human, internal fragment, T315I mutation, GST-HIS fusion protein, expressed in Sf9 cells

ABL1, ABL, JTK7, p150, c-ABL, v-abl
ProQinase™ ABL1 Y253F 0927-0000-1
Yes
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human, internal fragment, Y253F mutation, GST-HIS fusion protein, expressed in Sf9 cells

ABL1, ABL, JTK7, p150, c-ABL, v-abl
ProQinase™ ABL2 1548-0000-1
No
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human, N-terminal fragment, activated, GST-HIS fusion protein, expressed in Sf9 cells

ABL2, ABLL, ARG
ProQinase™ ACK1 0493-0000-1
Yes
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human, internal fragment, GST-HIS fusion protein, expressed in Sf9 cells

TNK2, ACK, p21cdc42Hs, Activated CDC42 kinase 1
ProQinase™ ACVR1 0372-0000-1
Yes
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human, C-terminal fragment, GST-HIS fusion protein, expressed in Sf9 cells

ACVR1, ACTRI, ACVRLK2, ALK2, SKR1, ACV-R1
ProQinase™ AKT1 1379-0000-2
Yes
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human, full length, activated, GST fusion protein, expressed in Sf9 cells

AKT1, PKB, RAC, PRKBA, RAC-ALPHA, AKT1 aa1-480
ProQinase™ AKT1 aa106-480 0132-0000-2
Yes
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human, C-terminal fragment, activated, GST-HIS fusion protein, expressed in Sf9 cells

AKT1, PKB, RAC, PRKBA, RAC-ALPHA
ProQinase™ AKT2 1577-0000-1
No
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human, full length, activated, GST fusion protein, expressed in Sf9 cells

AKT2, PKBB, PKBBETA, PKB beta, PRKBB, RAC-beta, RAC-PK-beta, AKT2 aa1-481
ProQinase™ AKT2 aa107-481 0276-0000-2
Yes
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human, C-terminal fragment, activated, GST-HIS fusion protein, expressed in Sf9 cells

AKT2, PKBB, PKBBETA, PKB beta, PRKBB, RAC-beta, RAC-PK-beta
ProQinase™ AKT3 1578-0000-1
Yes
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human, full length, activated, GST fusion protein, expressed in Sf9 cells

AKT3, PKBG, PKB gamma, PRKBG, RAC-gamma, RAC-PK-gamma, STK-2, DKFZp434N0250, AKT3 aa1-479
ProQinase™ AKT3 aa106-479 0436-0000-2
Yes
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human, C-terminal fragment, GST-HIS fusion protein, activated, expressed in Sf9 cells

AKT3, PKBG, PRKBG, STK-2, RAC-gamma, RAC-PK-gamma
ProQinase™ ALK 1176-0000-1
Yes
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human, internal fragment, GST-HIS fusion protein, expressed in Sf9 cells

ALK, CD246, NBLST3, ALK wt (GST-HIS-tag)
ProQinase™ ALK C1156Y 1177-0000-1
Yes
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human, internal fragment, C1156Y mutation, GST-HIS fusion protein, expressed in Sf9 cells

ALK, CD246, NBLST3, ALK C1156Y (GST-HIS-tag)
ProQinase™ ALK F1174L 1178-0000-1
Yes
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human, internal fragment, F1174L mutation, GST-HIS fusion protein, expressed in Sf9 cells

ALK, CD246, NBLST3, ALK F1174L (GST-HIS-tag)
ProQinase™ ALK F1174S 1179-0000-1
Yes
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human, internal fragment, F1174S mutation, GST-HIS fusion protein, expressed in Sf9 cells

ALK, CD246, NBLST3, ALK F1174S (GST-HIS-tag)
ProQinase™ ALK G1202R 1369-0000-1
Yes
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human, internal fragment, G1202R mutation, GST-HIS fusion protein, expressed in Sf9 cells

ALK, CD246, NBLST3, ALK G1202R (GST-HIS-tag)
ProQinase™ ALK L1196M 1180-0000-1
Yes
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human, internal fragment, L1196M mutation, GST-HIS fusion protein, expressed in Sf9 cells

ALK, CD246, NBLST3, ALK L1196M (GST-HIS-tag)
ProQinase™ ALK R1275Q 1181-0000-1
Yes
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human, internal fragment, R1275Q mutation, GST-HIS fusion protein, expressed in Sf9 cells

ALK, CD246, NBLST3, ALK R1275Q (GST-HIS-tag)
ProQinase™ AMPKalpha1 0289-0000-1
Yes
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human, full length, GST-HIS fusion protein, expressed in Sf9 cells

PRKAA1, MGC33776, MGC57364, AMPK-alpha1 aa1-550
ProQinase™ AMPKalpha1 aa1-312 0383-0000-1
No
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human, N-terminal fragment, GST-HIS fusion protein, expressed in Sf9 cells

PRKAA1, MGC33776, MGC57364, AMPK-alpha1 aa1-312
ProQinase™ ARAF YDYD 1768-0000-1
No
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human, C-terminal fragment, mutationally activated (Y301D; Y302D), GST-HIS fusion protein, expressed in Sf9 cells

ARAF, ARAF1
ProQinase™ ARK5 0300-0000-1
Yes
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human, full length, GST-HIS fusion protein, expressed in Sf9 cells

NUAK1, KIAA0537
ProQinase™ AuroraA 0166-0000-1
Yes
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human, full length, GST-HIS fusion protein, expressed in Sf9 cells

AURKA, AIK, ARK1, AURA, BTAK, STK15, MGC34538, STK6, Aurora-A
ProQinase™ AuroraB 0190-0000-1
Yes
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human, full-length, GST-HIS fusion protein, expressed in Sf9 cells

AURKB, AIK2, AIM1, ARK2, AurB, IPL1, STK5, AIM-1, STK12, Aurora-B
ProQinase™ AuroraC 0315-0000-1
Yes
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human, full length, GST-HIS fusion protein, expressed in Sf9 cells

AURKC, AIE2, AIK3, STK13, Aurora-C
ProQinase™ AXL 0525-0000-1
Yes
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human, C-terminal fragment, GST-HIS fusion protein, expressed in Sf9 cells

AXL, EC, UFO
ProQinase™ BLK 0448-0000-1
Yes
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human, full length, GST-HIS fusion protein, expressed in Sf9 cells

BLK, n/a
ProQinase™ BMPR1A 1655-0000-1
No
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human, C-terminal fragment, untagged, expressed in Sf9 cells

BMPR1A, SKR5, CD292, ALK3, ACVRLK3
ProQinase™ BMPR1B 1667-0000-1
Yes
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human, C-terminal fragment, GST-HIS fusion protein, expressed in Sf9 cells

BMPR1B, ALK6, CDw293
ProQinase™ BRAF 0403-0000-1
Yes
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human, C-terminal fragment, GST-HIS fusion protein, expressed in Sf9 cells

BRAF, B-Raf, B-raf-1, BRAF1, RAFB1, B-RAF wt
ProQinase™ BRAF V600E 0404-0000-1
Yes
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human, C-terminal fragment, mutationally activated (V600E), GST-HIS fusion protein, expressed in Sf9 cells

BRAF, B-Raf, B-raf-1, BRAF1, RAFB1, B-RAF V600E
ProQinase™ BRK 0181-0000-1
Yes
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human, full length, GST-HIS fusion protein, expressed in Sf9 cells

PTK6, n/a
ProQinase™ BRSK2 1524-0000-1
Yes
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human, full length, GST-HIS fusion protein, expressed in Sf9 cells

C11orf7, FLJ41362, HUSSY-12, PEN11B, SAD1, STK29
ProQinase™ BTK 0772-0000-2
Yes
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human, full length, GST fusion protein, expressed in Sf9 cells

BTK, AGMX1, AT, ATK, BPK, PSCTK1
ProQinase™ CCDC6 RET 1417-0000-1
Yes
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human, pathological fusionprotein, full-length, GST-HIS fusion protein, expressed in Sf9 cells

CCDC6-RET, CCDC6-RETa, CCDC6-RET
ProQinase™ CDC42BPB 0382-0000-1
No
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human, N-terminal fragment, GST-HIS fusion protein, expressed in Sf9 cells

CDC42BPB, MRCK-beta, MRCKb
ProQinase™ CDC7/DBF4 1513-1516-1
Yes
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human, full length, GST-HIS fusion proteins, expressed in Sf9 cells

CDC7, CDC7L1, HsCdc7, HsCDC7, Hsk1, huCdc7
ProQinase™ CDK1/CycA2 0134-0054-1
No
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human, full length, GST-HIS fusion proteins, expressed in Sf9 cells

CDC2, p34
ProQinase™ CDK1/CycB1 0134-0135-1
No
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human, full length, GST-HIS fusion proteins, expressed in Sf9 cells

CDC2, p34
ProQinase™ CDK1/CycE1 0134-0055-1
Yes
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human, full length, GST-HIS fusion proteins, expressed in Sf9 cells

CDC2, p34
ProQinase™ CDK10/CycQ 1527-1822-1
Yes
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human, full length, GST-HIS fusion proteins, expressed in Sf9 cells

CDK10, PISSLRE
ProQinase™ CDK12 R722C/CycK 1488-1484-1
No
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human, CDK12: internal fragment, R722C mutation, CycK: N-terminal fragment, GST-HIS fusion proteins, activated, expressed in Sf9 cells

CDK12, CRKRS, CRK7
ProQinase™ CDK12/CycK 1483-1484-1
No
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human, CDK12: internal fragment, CycK: N-terminal fragment, GST-HIS fusion proteins, activated, expressed in Sf9 cells

CDK12, CRKRS, CRK7, CDK12 wt/CycK
ProQinase™ CDK13/CycK 1530-1484-1
No
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human, CDK13: internal fragment, CycK: N-terminal fragment, GST-HIS fusion proteins, activated, expressed in Sf9 cells

CDK13, CDC2L, CDC2L5, CHED
ProQinase™ CDK16/CycY 1117-1116-1
No
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human, full length, CDK16: GST-HIS fusion protein, CycY: HIS fusion protein, expressed in Sf9 cells

CDK16, PCTAIRE1, PCTAIRE, PCTGAIRE, PCTK1
ProQinase™ CDK17/p35NCK 1526-0355-1
Yes
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human, full length, GST-HIS fusion proteins, expressed in Sf9 cells

CDK17, PCTAIRE2, PCTK2
ProQinase™ CDK18/CycY 1546-1619-1
Yes
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human, full length, GST-HIS fusion proteins, expressed in Sf9 cells

CDK18, PCTAIRE, PCTAIRE3, PCTK3
ProQinase™ CDK19/CycC 1384-0390-1
No
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human, full length, CDK19: GST-HIS fusion protein, CycC: HIS-tagged protein, expressed in Sf9 cells

CDK19, CDC2L6, CDK11
ProQinase™ CDK2/CycA2 0050-0054-1
Yes
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human, full length, GST-HIS fusion proteins, expressed in Sf9 cells

CDK2, p33(CDK2)
ProQinase™ CDK2/CycD1 0050-0143-1
No
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human, full length, GST-HIS fusion proteins, expressed in Sf9 cells

CDK2, p33
ProQinase™ CDK2/CycE1 0050-0055-1
Yes
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human, full length, GST-HIS fusion proteins, expressed in Sf9 cells

CDK2, p33(CDK2)
ProQinase™ CDK20/CycH 1528-0360-1
Yes
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human, full length, GST-HIS fusion proteins, expressed in Sf9 cells

CDK20, CAK-kinase p42
ProQinase™ CDK20/CycT1 1528-0345-1
Yes
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human, full length, GST-HIS fusion proteins, expressed in Sf9 cells

CDK20, CAK-kinase p42, CCRK, CDCH, p42, PNQALRE
ProQinase™ CDK3/CycC 0212-0390-1
No
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human, full length, CDK3: GST-HIS fusion protein, CycC: HIS-tagged protein, expressed in Sf9 cells

CDK3, CDKN3
ProQinase™ CDK3/CycE1 0212-0055-1
Yes
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human, full length, GST-HIS fusion proteins, expressed in Sf9 cells

CDK3, n/a
ProQinase™ CDK4/CycD1 0142-0143-1
Yes
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human, full length, GST-HIS fusion proteins, expressed in Sf9 cells

CDK4, CMM3, PSK-J3, MGC14458
ProQinase™ CDK4/CycD2 0142-0375-1
Yes
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human, full length, GST-HIS fusion proteins, expressed in Sf9 cells

CDK4, CMM3, PSK-J3
ProQinase™ CDK4/CycD3 0142-0373-1
Yes
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human, full length, CDK4: GST-HIS fusion protein, CycD3: HIS-tagged protein, expressed in Sf9 cells

CDK4, CMM3, PSK-J3, MGC14458
ProQinase™ CDK5/p25NCK 0356-0389-1
No
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human, full length, CDK5: GST-HIS fusion protein, p25NCK: HIS-tagged protein, expressed in Sf9 cells

CDK5, PSSALRE
ProQinase™ CDK5/p35NCK 0356-0355-1
Yes
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human, full length, CDK5: GST-HIS fusion protein, p35NCK: GST-HIS fusion protein, expressed in Sf9 cells

CDK5, PSSALRE
ProQinase™ CDK6/CycD1 0051-0143-2
Yes
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human, full length, GST-HIS fusion proteins, activated, expressed in Sf9 cells

CDK6, PLSTIRE, MGC59692
ProQinase™ CDK6/CycD2 0051-0375-1
Yes
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human, full length, GST-HIS fusion proteins, expressed in Sf9 cells

CDK6, PLSTIRE
ProQinase™ CDK6/CycD3 0051-0373-1
Yes
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human, full length, CDK6: GST-HIS fusion protein, CycD3: HIS-tagged protein, activated, expressed in Sf9 cells

CDK6, PLSTIRE
ProQinase™ CDK7/CycH/MAT1 0366-0360-4
Yes
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human, full length, CDK7: GST-HIS fusion protein, CycH/MAT1: HIS-tagged proteins, expressed in Sf9 cells

CDK7, CAK1, CDKN7, STK1, p39MO15
ProQinase™ CDK8/CycC 0376-0390-1
No
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human, full length, CDK8: GST-HIS fusion protein, CycC: HIS-tagged protein, expressed in Sf9 cells

CDK8, K35
ProQinase™ CDK9/CycK 0371-1484-1
Yes
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human, CDK9: full length, CycK: N-terminal fragment, GST-HIS fusion proteins, expressed in Sf9 cells

CDK9, C-2k, CDC2L4, PITALRE, TAK, CDC2-related kinase
ProQinase™ CDK9/CycT1 0371-0345-1
Yes
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human, full length, CDK9: GST-HIS fusion protein, CycT1: HIS-tagged protein, expressed in Sf9 cells

CDK9, C-2k, CDC2L4K35, PITALRE, TAK
ProQinase™ CHK1 0282-0000-1
No
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human, full length, GST-HIS fusion protein, expressed in Sf9 cells

CHEK1, n/a
ProQinase™ CK1alpha1 0406-0000-1
No
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human, full length, GST-HIS fusion protein, expressed in Sf9 cells

CSNK1A1, CK1, HLCDGP1, PRO2975, CK1-alpha1
ProQinase™ CK2alpha1 0124-0000-1
Yes
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human, full length, GST-HIS fusion protein, expressed in Sf9 cells

CSNK2A1, CKII, CK2A1, CK2-alpha1
ProQinase™ CK2alpha2 0412-0000-1
Yes
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human, full length, GST-HIS fusion protein, expressed in Sf9 cells

CSNK2A2, CK2-alpha2
ProQinase™ CLK1 0447-0000-1
No
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human, full length, GST-HIS fusion protein, expressed in Sf9 cells

CLK1, CLK, CLK/STY
ProQinase™ CLK3 0921-0000-1
Yes
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human, full-length, untagged, expressed in Sf9 cells

CLK3, PHCLK3, PHCLK3/152
ProQinase™ COT 0180-0000-1
No
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human, internal fragment, GST-HIS fusion protein, expressed in Sf9 cells

MAP3K8, EST, ESTF, TPL2, Tpl-2, c-COT
ProQinase™ CSF1R 0512-0000-1
Yes
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human, C-terminal fragment, activated, GST-HIS fusion protein, expressed in Sf9 cells

CSF1R, C-FMS, CD115, CSF-1-R, CSFR, FIM2, FMS, CSF1-R
ProQinase™ CSK 0266-0000-1
Yes
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human, full length, GST-HIS fusion protein, expressed in Sf9 cells

CSK, n/a
ProQinase™ DAPK1 0332-0000-1
Yes
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human, N-terminal fragment, GST-HIS fusion protein, expressed in Sf9 cells

DAPK1, n/a
ProQinase™ DDR2 0771-0000-1
Yes
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human, C-terminal fragment, activated, GST-HIS fusion protein, expressed in Sf9 cells

DDR2, MIG20a, NTRKR3, TKT, TYRO10, DDR2 wt
ProQinase™ DDR2 N456S 1190-0000-1
Yes
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human, C-terminal fragment, N456S mutation, activated, GST-HIS fusion protein, expressed in Sf9 cells

DDR2, MIG20a, NTRKR3, TKT, TYRO10
ProQinase™ DDR2 T654M 1193-0000-1
Yes
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human, C-terminal fragment, T654M mutation, activated, GST-HIS fusion protein, expressed in Sf9 cells

DDR2, MIG20a, NTRKR3, TKT, TYRO10
ProQinase™ EGFR 1033-0000-1
Yes
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human, C-terminal fragment, GST-HIS fusion protein, expressed in Sf9 cells

EGFR, ERBB, mENA, ERBB1, EGF-R wt
ProQinase™ EGFR C797S 1719-0000-1
Yes
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human, C-terminal fragment, C797S mutation, GST-HIS fusion protein, expressed in Sf9 cells

EGF-R, ERBB, ERBB1, EGF-R C797S
ProQinase™ EGFR C797S/L858R 1709-0000-1
Yes
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human, C-terminal fragment, C797S, L858R mutations, GST-HIS fusion protein, expressed in Sf9 insect cells

EGFR, ERBB, ERBB1, mENA, EGF-R C797S/L858R
ProQinase™ EGFR d746-750 1037-0000-1
Yes
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human, C-terminal fragment, D746-750 mutation, GST-HIS fusion protein, expressed in Sf9 cells

EGFR, ERBB, mENA, ERBB1, EGF-R d746-750
ProQinase™ EGFR d746-750/C797S 1706-0000-1
Yes
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human, C-terminal fragment, d746-750, C797S mutation, GST-HIS fusion protein, expressed in Sf9 insect cells

EGFR, ERBB, ERBB1, EGF-R, mENA
ProQinase™ EGFR d746-750/T790M/C797S 1715-0000-1
Yes
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human, C-terminal fragment, D746-750,T790M, C797S mutations, GST-HIS fusion protein, expressed in Sf9 insect cells

EGFR, ERBB, ERBB1, mENA, EGF-R d746-750/T790M/C797S
ProQinase™ EGFR d746-750/T790M/C797S/L858R 1712-0000-1
Yes
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human, C-terminal fragment, D746-750,T790M, C797S, L858R mutations, GST-HIS fusion protein, expressed in Sf9 insect cells

EGFR, ERBB, mENA, ERBB1, EGF-R d746-750/T790M/C797S/L858R
ProQinase™ EGFR d747-749/A750P 1038-0000-1
Yes
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human, C-terminal fragment, D747-749/A750P mutation, GST-HIS fusion protein, expressed in Sf9 cells

EGFR, ERBB, mENA, ERBB1, EGF-R d747-749/A750P
ProQinase™ EGFR d747-752/P753S 1039-0000-1
Yes
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human, C-terminal fragment, D747-752/P753S mutation, GST-HIS fusion protein, expressed in Sf9 cells

EGFR, ERBB, mENA, ERBB1, EGF-R d747-752/P753S
ProQinase™ EGFR d752-759 1040-0000-1
Yes
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human, C-terminal fragment, D752-759 mutation, GST-HIS fusion protein, expressed in Sf9 cells

EGFR, ERBB, mENA, ERBB1, EGF-R d752-759
ProQinase™ EGFR G719C 1034-0000-1
Yes
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human, C-terminal fragment, G719C mutation, GST-HIS fusion protein, expressed in Sf9 cells

EGFR, ERBB, mENA, ERBB1, EGF-R G719C
ProQinase™ EGFR G719S 1035-0000-1
Yes
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human, C-terminal fragment, G719S mutation, GST-HIS fusion protein, expressed in Sf9 cells

EGFR, ERBB, mENA, ERBB1, EGF-R G719S
ProQinase™ EGFR L718Q 1747-0000-1
No
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human, C-terminal fragment, L718Q mutation, GST-HIS fusion protein, expressed in Sf9 insect cells

EGFR, ERBB, ERBB1, mENA, EGF-R L718Q
ProQinase™ EGFR L858R 0724-0000-1
Yes
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human, C-terminal fragment, L858R mutation, GST-HIS fusion protein, expressed in Sf9 cells

EGFR, ERBB, ERBB1, EGF-R L858R
ProQinase™ EGFR L861Q 1036-0000-1
Yes
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human, C-terminal fragment, L861Q mutation, GST-HIS fusion protein, expressed in Sf9 cells

EGFR, ERBB, mENA, ERBB1, EGF-R L861Q
ProQinase™ EGFR T790M 0758-0000-1
Yes
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human, C-terminal fragment, T790M gatekeeper mutation, GST-HIS fusion protein, expressed in Sf9 cells

EGFR, ERBB, ERBB1, EGF-R T790M
ProQinase™ EGFR T790M/C797S/L858R 1701-0000-1
Yes
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EGFR, ERBB, ERBB1, EGF-R T790M/C797S/L858R
ProQinase™ EGFR T790M/L858R 0725-0000-1
Yes
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human, C-terminal fragment, T790M/L858R mutation, GST-HIS fusion protein, expressed in Sf9 cells

EGFR, ERBB, ERBB1, EGF-R T790M/L858R
ProQinase™ EML4 ALK 1246-0000-1
Yes
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human, full length, GST fusion protein, expressed in Sf9 cells

ALK
ProQinase™ EML4 ALK F1174L 1247-0000-1
Yes
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human, full length, GST fusion protein, expressed in Sf9 cells

ALK
ProQinase™ EPHA1 0215-0000-1
Yes
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human, C-terminal fragment, GST-HIS fusion protein, expressed in Sf9 cells

EPHA1, EPH, EPHT, EPHT1
ProQinase™ EPHA2 0368-0000-1
Yes
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human, C-terminal fragment,GST-HIS fusion protein, expressed in Sf9 cells

EPHA2, ECK
ProQinase™ EPHA3 0351-0000-1
Yes
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human, C-terminal fragment, GST-HIS fusion protein, expressed in Sf9 cells

EPHA3, ETK, ETK1, EphA3, HEKECK, HEK4, TYRO4
ProQinase™ EPHA4 0334-0000-1
Yes
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human, C-terminal fragment, GST-HIS fusion protein, expressed in Sf9 cells

EPHA4, HEK8, SEK, TYRO1
ProQinase™ EPHA5 0739-0000-1
Yes
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human, C-terminal fragment, activated, GST-HIS fusion protein, expressed in Sf9 cells

EPHA5, CEK7, EHK1, EphA5, HEK7, Hek7, TYRO4
ProQinase™ EPHA6 1515-0000-1
Yes
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human, C-terminal fragment, GST-HIS fusion protein, expressed in Sf9 cells

EPHA6, EHK2, EHK-2, EPA6
ProQinase™ EPHA7 0741-0000-1
Yes
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human, C-terminal fragment, activated, GST-HIS fusion protein, expressed in Sf9 cells

EPHA7, EHK3, HEK11
ProQinase™ EPHB1 0317-0000-1
Yes
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human, C-terminal fragment, GST-HIS fusion protein, expressed in Sf9 cells

EPHB1, ELK, NET, Hek6, EPHT2
ProQinase™ EPHB2 0194-0000-3
Yes
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human, C-terminal fragment, activated, GST-HIS fusion protein, expressed in Sf9 cells

EPHB2, DRT, ERK, Hek5, EPHT3, Tyro5
ProQinase™ EPHB3 0231-0000-1
Yes
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human, C-terminal fragment, GST-HIS fusion protein, expressed in Sf9 cells

EPHB3, ETK2, HEK2, TYRO6
ProQinase™ EPHB4 0178-0000-3
Yes
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human, C-terminal fragment, activated, GST-HIS fusion protein, expressed in Sf9 cells

EPHB4, HTK, MYK1, TYRO11
ProQinase™ ERBB2 0108-0000-1
Yes
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human, C-terminal fragment, GST-HIS fusion protein, expressed in Sf9 cells

ERBB2, NEU, NGL, HER2, TKR1, HER-2, ERBB2 wt
ProQinase™ ERBB2 775YVMA776 1525-0000-1
Yes
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human, C-terminal fragment, aa 723-725 internal tandem duplication, GST-HIS fusion protein, expressed in Sf9 cells

ERBB2, CD340, HER2, MLN19, NGL, TKR1
ProQinase™ ERBB4 0109-0000-1
Yes
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human, C-terminal fragment, GST-HIS fusion protein, expressed in Sf9 cells

ERBB4, n/a
ProQinase™ ERK1 0883-0000-1
Yes
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human, full length, activated, GST fusion protein, expressed in E.coli

MAPK3, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3
ProQinase™ ERK2 0634-0000-7
Yes
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human, full length, activated, untagged, expressed in E.coli

MAPK1, ERK, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41
ProQinase™ ERK5 1105-0000-1
Yes
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human, internal fragment, N-terminal FLAG, C-terminal HIS8 fusion protein, expressed in Sf9 cells

MAPK7, BMK1, ERK4, PRKM7
ProQinase™ ERK7 1106-0000-2
Yes
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human, N-terminal fragment, activated, N-terminal FLAG, C-terminal HIS8-tagged fusion protein, expressed in Sf9 cells

MAPK15, ERK8, MAPK15
ProQinase™ FAK 0165-0000-3
Yes
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human, full-length, activated, GST fusion protein, expressed in Sf9 cells

PTK2, FADK, pp125FAK, FAK aa2-1052
ProQinase™ FAK aa411-686 0480-0000-6
No
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human, internal fragment,untagged, expressed in E.coli

PTK2, FADK, pp125FAK
ProQinase™ FER 0533-0000-1
Yes
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human, C-terminal fragment, GST-HIS fusion protein, expressed in Sf9 cells

FER, TYK3, c-FER, p94-FER
ProQinase™ FGFR1 0101-0000-1
Yes
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human, C-terminal fragment, GST-HIS fusion protein, expressed in Sf9 cells

FGFR1, H2, H3, H4, H5, CEK, FLG, FLT2, KAL2, BFGFR, C-FGR, N-SAM, FGF-R1 wt
ProQinase™ FGFR1 V561M 0890-0000-1
Yes
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human, internal fragment, V561M mutation, untagged, expressed in Sf9 cells

FGFR1, FGFR-1, bFGF-R, FLT2, CEK, CD331, FGF-R1 V561M
ProQinase™ FGFR2 1404-0000-1
Yes
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human, C-terminal fragment, GST-HIS fusion protein, expressed in Sf9 cells

FGFR2, FGFR2, BEK, BFR-1, CD332, CEK3, CFD1, ECT1, FGFR-2, JWS, KGFR, KSAM, K-SAM, TK14, TK25
ProQinase™ FGFR3 1068-0000-1
Yes
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human, C-terminal fragment, GST-HIS fusion protein, expressed in Sf9 cells

FGFR3, ACH, CD333, CEK2, FGFR-3, HSFGFR3EX, JTK4, FGF-R3 wt
ProQinase™ FGFR3 G697C 1071-0000-1
Yes
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human, C-terminal fragment, G697C mutation, GST-HIS fusion protein, expressed in Sf9 cells

FGFR3, ACH, CD333, CEK2, FGFR-3, HSFGFR3EX, JTK4, FGF-R3 G697C
ProQinase™ FGFR3 K650E 1070-0000-1
Yes
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human, C-terminal fragment, K650E mutation, GST-HIS fusion protein, expressed in Sf9 cells

FGFR3, ACH, CD333, CEK2, FGFR-3, HSFGFR3EX, JTK4, FGF-R3 K650E
ProQinase™ FGFR3 K650M 1069-0000-1
Yes
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human, C-terminal fragment, K650E mutation, GST-HIS fusion protein, expressed in Sf9 cells

FGFR3, ACH, CD333, CEK2, FGFR-3, HSFGFR3EX, JTK4, FGF-R3 K650M
ProQinase™ FGFR4 0127-0000-3
Yes
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human, C-terminal fragment, activated, GST-HIS fusion protein, expressed in Sf9 cells

FGFR4, TKF, JTK2, MGC20292, FGF-R4
ProQinase™ FGR 0234-0000-1
No
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human, full length, GST-HIS fusion protein, expressed in Sf9 cells

FGR, SRC2, c-fgr, p55c-fgr
ProQinase™ FLT3 0776-0000-1
Yes
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human, C-terminal fragment, GST-HIS fusion protein, expressed in Sf9 cells

FLT3, CD135, FLK2, STK-1, STK1, FLT3 wt
ProQinase™ FLT3 D835Y 0777-0000-1
Yes
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human, C-terminal fragment, D835Y mutation, GST-HIS fusion protein, expressed in Sf9 cells

FLT3, CD135, FLK2, STK-1, STK1
ProQinase™ FLT3 ITD 0778-0000-1
Yes
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human, C-terminal fragment, aa 591-601internal tandem duplication, GST-HIS fusion protein, expressed in Sf9 cells

FLT3, CD135, FLK2, STK-1, STK1
ProQinase™ FRK 0446-0000-1
Yes
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human, full length, GST-HIS fusion protein, expressed in Sf9 cells

FRK, GTK, PTK5, RAK
ProQinase™ FYN 0352-0000-1
Yes
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human, full length, GST-HIS fusion protein, expressed in Sf9 cells

FYN, SLK, SYN, p59-Fyn, FYN wt
ProQinase™ FYN Y531F 1457-0000-1
Yes
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human, full length, Y531F mutation, GST-HIS fusion protein, expressed in Sf9 cells

FYN, SLK, SYN, p59-FYN, cFYN
ProQinase™ GSG2 1319-0000-1
Yes
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human, C-terminal fragment, HIS fusion protein, expressed in E.coli

GSG2, Haspin
ProQinase™ GSK3beta 0310-0000-1
No
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human, full length,GST-HIS fusion protein, expressed in Sf9 cells

GSK3B, GSK3-beta
ProQinase™ HCK 0408-0000-1
Yes
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human, full length, GST-HIS fusion protein, expressed in Sf9 cells

HCK, JTK9
ProQinase™ HIPK3 0936-0000-1
No
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human, internal fragment, activated, untagged, expressed in Sf9 cells

HIPK3, ANPK, DYRK6, FIST, FIST3, PKY, YAK1
ProQinase™ HRI 0444-0000-1
No
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human, full length, GST-HIS fusion protein, expressed in Sf9 cells

EIF2AK1, HCR
ProQinase™ IGF1R 0179-0000-1
Yes
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human, C-terminal fragment, GST-HIS fusion protein, expressed in Sf9 cells

IGF1R, JTK13, IGF1-R
ProQinase™ IKKbeta 0258-0000-1
Yes
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human, full length, GST-HIS fusion protein, expressed in Sf9 cells

IKBKB, IKK2, IKKB, NFKBIKB, IKK-beta
ProQinase™ IKKepsilon 0320-0000-1
Yes
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human, full length, GST-HIS fusion protein, expressed in Sf9 cells

IKBKE, IKKE, IKKI, IKK-i, KIAA0151, IKK-epsilon
ProQinase™ INSR 0122-0000-1
Yes
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human, C-terminal fragment, GST fusion protein, expressed in Sf9 cells

INSR, INS-R
ProQinase™ IRAK4 1752-0000-1
Yes
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human, full length, GST-HIS fusion protein, expressed in Sf9 cells

IRAK4, REN64, NY-REN-64
ProQinase™ IRAK4 aa104-460 0268-0000-1
No
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human, C-terminal fragment, GST-HIS fusion protein, expressed in Sf9 cells

IRAK4, REN64, NY-REN-64
ProQinase™ IRAK4 aa104-460 (untagged) 0586-0000-1
Yes
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human, C-terminal fragment, untagged, expressed in Sf9 cells

IRAK4, REN64, NY-REN-64
ProQinase™ ITK 0359-0000-1
No
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human, full length, GST-HIS fusion protein, expressed in Sf9 cells

ITK, EMT 2, LYK 2, PSCTK2 2, IL2-inducible T-cell kinase
ProQinase™ JAK1 1480-0000-1
Yes
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human, C-terminal fragment, GST-HIS fusion protein, expressed in Sf9 cells

JAK1, JAK1A, JAK1B, JTK3, JAK1 aa583-1154 wt
ProQinase™ JAK1 aa850-1154 0773-0000-1
Yes
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human, C-terminal fragment, GST-HIS fusion protein, expressed in Sf9 cells

JAK1, JAK-1, JAK1A, AK1B, JAK1 aa850-1154 wt
ProQinase™ JAK1 S729C 1481-0000-1
Yes
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human, C-terminal fragment, S729C mutation, GST-HIS fusion protein, expressed in Sf9 cells

JAK1, JAK1A, JAK1B, JTK3, JAK1 aa583-1154 S729C
ProQinase™ JAK2 0646-0000-1
Yes
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human, C-terminal fragment, GST-HIS fusion protein, expressed in Sf9 cells

JAK2, n/a
ProQinase™ JAK3 0354-0000-1
No
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human, C-terminal fragment, GST-HIS fusion protein, expressed in Sf9 cells

JAK3, JAKL, L-JAK, LJAK
ProQinase™ JNK1 0458-0000-1
Yes
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human, full length, activated, untagged, expressed in E.coli

MAPK8, PRKM8, SAPK1, JNK1-alpha1
ProQinase™ JNK2 0459-0000-1
Yes
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human, full length, activated, untagged, expressed in E.coli

MAPK9, PRKM9, p54aSAPK, JNK2-alpha2
ProQinase™ JNK3 0900-0000-1
Yes
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human, full length, activated, untagged, expressed in E.coli

MAPK10, JNK3A, p54bSAPK
ProQinase™ KIT 0997-0000-1
Yes
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human, C-terminal fragment, activated, GST-HIS fusion protein, expressed in Sf9 cells

KIT, C-Kit, PBT, CD117, SCFR, c-kit, KIT wt
ProQinase™ KIT A829P 1042-0000-1
Yes
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human, C-terminal fragment, activated, A829P mutation, GST-HIS fusion protein, expressed in Sf9 cells

KIT, C-Kit, PBT, CD117, SCFR, c-kit
ProQinase™ KIT D816H 1041-0000-1
Yes
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human, C-terminal fragment, activated, D816H mutation, GST-HIS fusion protein, expressed in Sf9 cells

KIT, C-Kit, PBT, CD117, SCFR, c-kit
ProQinase™ KIT D816V 0946-0000-1
Yes
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human, C-terminal fragment, activated, D816V mutation, GST-HIS fusion protein, expressed in Sf9 cells

KIT, C-Kit, PBT, CD117, SCFR, c-kit
ProQinase™ KIT T670I 0759-0000-1
Yes
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human, C-terminal fragment, activated, T670I gatekeeper mutation, GST-HIS fusion protein, expressed in Sf9 cells

KIT, CD117, SCFR, PBT, C-Kit
ProQinase™ KIT V559D 1047-0000-1
Yes
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human, C-terminal fragment, activated, V559D mutation, GST-HIS fusion protein, expressed in Sf9 cells

KIT, C-Kit, PBT, CD117, SCFR, c-kit
ProQinase™ KIT V559D/T670I 1044-0000-1
Yes
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human, C-terminal fragment, activated, V559D/T670I mutation, GST-HIS fusion protein, expressed in Sf9 cells

KIT, C-Kit, PBT, CD117, SCFR, c-kit
ProQinase™ KIT V559D/V654A 1045-0000-1
Yes
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human, C-terminal fragment, activated, V559D/V654A mutation, GST-HIS fusion protein, expressed in Sf9 cells

KIT, C-Kit, PBT, CD117, SCFR, c-kit
ProQinase™ KIT V560G 1046-0000-1
Yes
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human, C-terminal fragment, activated, V560G mutation, GST-HIS fusion protein, expressed in Sf9 cells

KIT, C-Kit, PBT, CD117, SCFR, c-kit
ProQinase™ KIT V654A 0947-0000-1
Yes
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human, C-terminal fragment, activated, V654A mutation, GST-HIS fusion protein, expressed in Sf9 cells

KIT, C-Kit, PBT, CD117, SCFR, c-kit
ProQinase™ LCK 0238-0000-1
Yes
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human, full length, GST-HIS fusion protein, expressed in Sf9 cells

LCK, n/a
ProQinase™ LYN 0358-0000-1
Yes
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human, full length, GST-HIS fusion protein, expressed in Sf9 cells

LYN, JTK8
ProQinase™ MAP3K1 1103-0000-1
No
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human, C-terminal fragment, N-terminal FLAG, C-terminal HIS8-tagged fusion protein, expressed in Sf9 cells

MAP3K1, MAPKKK1, MEKK, MEKK1
ProQinase™ MAP4K4 1493-0000-1
Yes
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human, full length, GST-HIS fusion protein, expressed in Sf9 cells

MAP4K4, HGK, MEKKK4, NIK
ProQinase™ MAPKAPK2 0937-0000-1
Yes
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human, full length, activated, untagged, expressed in Sf9 cells

MAPKAPK2, n/a
ProQinase™ MAPKAPK3 0633-0000-1
No
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human, full length, activated, untagged, expressed in E.coli

MAPKAPK3, 3PK, MAPKAP, MAPKAP3
ProQinase™ MAPKAPK5 0712-0000-1
No
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human, full length, activated, untagged, expressed in E.coli

MAPKAPK5, PRAK
ProQinase™ MARK1 0432-0000-1
No
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human, full length, GST-HIS fusion protein, expressed in Sf9 cells

MARK1, KIAA1477
ProQinase™ MARK3 0433-0000-1
No
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human, full length, GST-HIS fusion protein, expressed in Sf9 cells

MARK3, CTAK1, KP78, PAR1A
ProQinase™ MASTL 1593-0000-2
Yes
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human, full length, GST-HIS fusion protein, activated, expressed in Sf9 cells

MASTL, GLW, GREATWALL, GWL, hGWL, MAST-L, THC2
ProQinase™ MEK1 0550-0000-3
Yes
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human, full length, activated, untagged, expressed in Sf9 cells

MAP2K1, MAPKK1, MKK1, PRKMK1, MEK1 wt
ProQinase™ MEK1 F53L 1538-0000-1
No
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human, full length, F53L mutation, activated, untagged, expressed in Sf9 cells

MAP2K1, MAP2K1, MAPKK1, MAPKK 1, MKK1, PRKMK1
ProQinase™ MEK1 SESE 0385-0000-1
No
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human, C-terminal fragment, mutationally activated (S218E, S222E), GST-HIS fusion protein, expressed in Sf9 cells

MAP2K1, MAPKK1, MKK1, PRKMK1, MEK1 S218E/S222E
ProQinase™ MEK5 0626-0000-1
Yes
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human, C-terminal fragment, N-terminal HIS-tagged protein, expressed in Sf9 cells

MAP2K5, MAP2K5, MAPKK5, MKK5, PRKMK5
ProQinase™ MEKK2 0583-0000-1
Yes
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human, full length, activated, GST-HIS fusion protein, expressed in Sf9 cells

MAP3K2, MAPKKK2, MEKK2B
ProQinase™ MEKK3 0859-0000-1
Yes
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human, full length, activated, GST-HIS fusion protein, expressed in Sf9 cells

MAP3K3, MAPKKK3, MEK kinase3
ProQinase™ MELK 0662-0000-1
Yes
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human, N-terminal fragment, untagged, expressed in Sf9 cells

MELK, PK38
ProQinase™ MERTK 0770-0000-1
Yes
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human, C-terminal fragment, GST-HIS fusion protein, expressed in Sf9 cells

MERTK, MER, MER-PEN, RP38
ProQinase™ MET 0171-0000-1
Yes
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human, C-terminal fragment, GST-HIS fusion protein, expressed in Sf9 cells

MET, HGFR, RCCP2, MET wt
ProQinase™ MET D1228H 0995-0000-1
Yes
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human, C-terminal fragment, D1228H mutation, GST-HIS fusion protein, expressed in Sf9 cells

MET, HGFR, RCCP2
ProQinase™ MET D1228N 0994-0000-1
Yes
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human, C-terminal fragment, D1228N mutation, GST-HIS fusion protein, expressed in Sf9 cells

MET, HGFR, RCCP2
ProQinase™ MET F1200I 0978-0000-1
Yes
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human, C-terminal fragment, F1200I mutation, GST-HIS fusion protein, expressed in Sf9 cells

MET, HGFR, RCCP2
ProQinase™ MET G1163R 1650-0000-1
Yes
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human, C-terminal fragment, G1163R  mutation, GST-HIS fusion protein, expressed in Sf9 cells

MET, HGFR, RCCP2
ProQinase™ MET L1195V 1651-0000-1
Yes
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human, C-terminal fragment, L1195V mutation, GST-HIS fusion protein, expressed in Sf9 cells

MET, HGFR, RCCP2
ProQinase™ MET M1250T 0982-0000-1
Yes
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human, C-terminal fragment, M1250T mutation, GST-HIS fusion protein, expressed in Sf9 cells

MET, HGFR, RCCP2
ProQinase™ MET Y1230A 0944-0000-1
Yes
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human, C-terminal fragment, Y1230A mutation, GST-HIS fusion protein, expressed in Sf9 cells

MET, HGFR, RCCP2
ProQinase™ MET Y1230C 0980-0000-1
Yes
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human, C-terminal fragment, Y1230C mutation, GST-HIS fusion protein, expressed in Sf9 cells

MET, HGFR, RCCP2
ProQinase™ MET Y1230D 0981-0000-1
Yes
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human, C-terminal fragment, Y1230D mutation, GST-HIS fusion protein, expressed in Sf9 cells

MET, HGFR, RCCP2
ProQinase™ MET Y1230H 0976-0000-1
Yes
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human, C-terminal fragment, Y1230H mutation, GST-HIS fusion protein, expressed in Sf9 cells

MET, HGFR, RCCP2
ProQinase™ MET Y1235D 0993-0000-1
Yes
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human, C-terminal fragment, Y1235D mutation, GST-HIS fusion protein, expressed in Sf9 cells

MET, HGFR, RCCP2
ProQinase™ MINK1 0698-0000-1
Yes
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human, N-terminal fragment, GST-HIS fusion protein, expressed in Sf9 cells

MINK1, B55, YSK2, MAP4K6, ZC3
ProQinase™ MKK4 0948-0000-1
No
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human, full length, activated, HIS fusion protein, expressed in Sf9 cells

MAP2K4, JNKK, JNKK1, MAPKK4, MEK4, PRKMK4, SEK, SERK1
ProQinase™ MKK6 SDTD 0396-0000-1
Yes
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human, full length, mutationally activated (S207D, T211D), GST-HIS fusion protein, expressed in Sf9 cells

MAP2K6, MAPKK6, MEK6, MKK6, PRKMK6, SAPKK3, MKK6 S207D/T211D
ProQinase™ MKK7 0726-0000-1
No
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human, full length, activated, GST-HIS fusion protein, expressed in Sf9 cells

MAP2K7, MAPKK7, MEK7, PRKMK7
ProQinase™ MLK4 1078-0000-1
Yes
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human, internal fragment, GST-HIS fusion protein, expressed in Sf9 cells

n/a, KIAA1804
ProQinase™ MST1 0667-0000-1
Yes
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human, aa 3-487, GST-HIS fusion protein, expressed in Sf9 cells

STK4, KRS2, YSK3
ProQinase™ MST2 0699-0000-1
Yes
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human, full length, untagged, expressed in Sf9 cells

STK3, MST-2, KRS1
ProQinase™ MST4 0286-0000-1
Yes
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human, full length, GST-HIS fusion protein, expressed in Sf9 cells

MST4, MASK
ProQinase™ MUSK 0226-0000-3
Yes
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human, C-terminal fragment, activated, GST-HIS fusion protein, expressed in Sf9 cells

MUSK, n/a
ProQinase™ MYLK2 0445-0000-1
Yes
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human, full length, GST-HIS fusion protein, expressed in Sf9 cells

MYLK2, KMLC, MLCK, skMLCK
ProQinase™ NDR1 1775-0000-1
Yes
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human, full length, GST-HIS fusion protein, expressed in Sf9 cells

STK38, NDR, NDR-LSB
ProQinase™ NDR2 1776-0000-1
Yes
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human, full-length, GST-HIS fusion protein, expressed in Sf9 cells

STK38L, KIAA0965
ProQinase™ NEK1 0844-0000-1
No
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human, N-terminal fragment, activated, GST-HIS fusion protein, expressed in Sf9 cells

NEK1, NY-REN-55
ProQinase™ NEK2 0290-0000-1
No
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human, full length, GST-HIS fusion protein, expressed in Sf9 cells

NEK2, NLK1, HsPK21, HsPK 21
ProQinase™ NEK3 1624-0000-1
Yes
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human, full length, GST-HIS fusion protein, expressed in Sf9 cells

NEK3, HSPK36, MGC29949
ProQinase™ NEK6 0209-0000-1
Yes
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human, C-terminal fragment, GST-HIS fusion protein, expressed in Sf9 cells

NEK6, SID6-1512
ProQinase™ NEK7 0669-0000-1
Yes
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human, full length, GST-HIS fusion protein, expressed in Sf9 cells

NEK7, n/a
ProQinase™ NIK 0344-0000-1
No
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human, full length, GST-HIS fusion protein, expressed in Sf9 cells

MAP3K14, FTDCR1B, HS, HSNIK
ProQinase™ NLK 0253-0000-1
No
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human, full length, GST-HIS fusion protein, expressed in Sf9 cells

NLK, n/a
ProQinase™ NPM1 ALK 1236-0000-1
Yes
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human, pathological fusionprotein, full-length, untagged, expressed in Sf9 cells

n/a, n/a
ProQinase™ NPM1 ALK F1174L 1281-0000-1
Yes
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human, pathological fusionprotein, full-length, F1174L mutation, untagged, expressed in Sf9 cells

n/a, n/a
ProQinase™ p38alpha 0443-0000-3
Yes
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human, full length, activated, untagged, expressed in E.coli

MAPK14, p38-alpha
ProQinase™ p38beta 0455-0000-3
Yes
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human, full length, activated, untagged, expressed in E.coli

MAPK11, p38-beta
ProQinase™ p38delta 0941-0000-1
Yes
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human, full length, activated, untagged, expressed in E.coli

MAPK13, p38-delta
ProQinase™ p38gamma 0958-0000-1
No
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human, full-length, untagged, expressed in E.coli

MAPK12, ERK-6, ERK3, ERK5, ERK6, PRKM12, SAPK-3, SAPK3, p38-gamma
ProQinase™ PAK1 0357-0000-1
Yes
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human, full length, GST-HIS fusion protein, expressed in Sf9 cells

PAK1, PAKalpha
ProQinase™ PAK2 0304-0000-1
Yes
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human, C-terminal fragment, GST-HIS fusion protein, expressed in Sf9 cells

PAK2, PAK65, PAKgamma
ProQinase™ PAK3 0422-0000-1
No
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human, full length, GST-HIS fusion protein, expressed in Sf9 cells

PAK3, CDKN1A, MRX30, OPHN3, PAK3beta, bPAK, hPAK3
ProQinase™ PAK4 0365-0000-1
No
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human, full length, GST-HIS fusion protein, expressed in Sf9 cells

PAK4, n/a
ProQinase™ PAK6 0423-0000-1
Yes
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human, full length, GST-HIS fusion protein, expressed in Sf9 cells

PAK6, PAK5
ProQinase™ PAK7 0410-0000-1
Yes
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human, full length, GST-HIS fusion protein, expressed in Sf9 cells

PAK7, KIAA1264, MGC26232
ProQinase™ PBK 0185-0000-2
No
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human, full length, GST-HIS fusion protein, expressed in Sf9 cells

PBK, TOPK, SPK, Nori-3, FLJ14385
ProQinase™ PDGFRalpha 1057-0000-1
Yes
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human, C-terminal fragment, GST-HIS fusion protein, expressed in Sf9 cells

PDGFRA, PDGFR2, CD140a, PDGFR-alpha wt
ProQinase™ PDGFRalpha D842V 0761-0000-1
Yes
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human, C-terminal fragment, D842V mutation, GST-HIS fusion protein, expressed in Sf9 cells

PDGFRA, PDGFR2, CD140a, PDGFR-alpha D842V
ProQinase™ PDGFRalpha T674I 0760-0000-1
Yes
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human, C-terminal fragment, T674I mutation, GST-HIS fusion protein, expressed in Sf9 cells

PDGFRA, PDGFR2, CD140a, PDGFR-alpha T674I
ProQinase™ PDGFRalpha V561D 1056-0000-1
Yes
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human, C-terminal fragment, V561D mutation, GST-HIS fusion protein, expressed in Sf9 cells

PDGFRA, PDGFR2, CD140a, PDGFR-alpha V561D
ProQinase™ PDGFRbeta 0099-0000-1
Yes
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human, C-terminal fragment, GST fusion protein, expressed in Sf9 cells

PDGFRB, JTK12, PDGFR, CD140B, PDGFR1, PDGF-R-beta, PDGFR-beta
ProQinase™ PDK1 0367-0000-1
No
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human, N-terminal fragment, N-terminal HIS-tagged protein, expressed in Sf9 cells

PDPK1, PKB-like
ProQinase™ PIM1 0186-0000-1
Yes
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human, full length, GST-HIS fusion protein, expressed in Sf9 cells

PIM1, PIM
ProQinase™ PIM2 0223-0000-1
Yes
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human, full length, GST-HIS fusion protein, expressed in Sf9 cells

PIM2, n/a
ProQinase™ PIM3 0932-0000-1
Yes
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human, full length, GST-HIS fusion protein, expressed in Sf9 cells

PIM3, n/a
ProQinase™ PKCalpha 0222-0000-1
Yes
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human, full length, GST-HIS fusion protein, expressed in Sf9 cells

PRKCA, PKCA, PRKACA, PKC-alpha
ProQinase™ PKCbeta1 0067-0000-1
Yes
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human, full length, GST fusion protein, expressed in Sf9 cells

PRKCB1, PKCB, PRKCB, PRKCB2, MGC41878, PKC-beta, PKC-beta1
ProQinase™ PKCbeta2 0116-0000-1
Yes
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human, full length, GST fusion protein, expressed in Sf9 cells

PRKCB1, PKCB, PRKCB, PRKCB2, MGC41878, PKC-beta, PKC-beta2
ProQinase™ PKCdelta 0232-0000-1
Yes
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human, full length, GST-HIS fusion protein, expressed in Sf9 cells

PRKCD, MAY1, MGC49908, nPKC-delta, PKC-delta
ProQinase™ PKCepsilon 0203-0000-1
Yes
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human, full length, GST-HIS fusion protein, expressed in Sf9 cells

PRKCE, PKCE, nPKC-epsilon, PKC-epsilon
ProQinase™ PKCeta 0420-0000-1
No
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human, full length, GST-HIS fusion protein, expressed in Sf9 cells

PRKCH, PKC-L, PKCL, PRKCL, nPKC-eta, PKC-eta
ProQinase™ PKCgamma 0204-0000-1
Yes
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human, full length, GST-HIS fusion protein, expressed in Sf9 cells

PRKCG, PKCC, PKCG, SCA14, MGC57564, PKC-gamma
ProQinase™ PKCiota 0114-0000-1
Yes
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human, full length, GST-HIS fusion protein, expressed in Sf9 cells

PRKCI, PKCI, DXS1179E, MGC26534, nPKC-iota, PKC-iota
ProQinase™ PKCmu 0115-0000-1
Yes
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human, full length, GST-HIS fusion protein, expressed in Sf9 cells

PRKD1, PKD, PKCM, PKC-MU, PKC-mu
ProQinase™ PKCnu 0661-0000-1
Yes
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human, aa 3-890, untagged, expressed in Sf9 cells

PRKD3, EPK2, PKC-nu
ProQinase™ PKCtheta 0113-0000-1
Yes
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human, full length, GST-HIS fusion protein, expressed in Sf9 cells

PRKCQ, PRKCT, nPKC-theta, PKC-theta
ProQinase™ PKCzeta 0117-0000-1
Yes
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human, C-terminal fragment, GST-HIS fusion protein, expressed in Sf9 cells

PRKCZ, PKC2, PKC-zeta
ProQinase™ PKMYT1 1521-0000-1
Yes
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human, full length, GST-HIS fusion protein, expressed in Sf9 cells

PKMYT1, MYT1
ProQinase™ PKMzeta 1240-0000-1
Yes
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human, C-terminal fragment (termed PKM-zeta), GST-HIS fusion protein, expressed in Sf9 cells

PRKCZ, PKM-zeta, nPKC-zeta, PKC2, PKC-zeta wt aa184-592 (PKM-zeta)
ProQinase™ PLK1 0183-0000-1
Yes
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human, full length, GST-HIS fusion protein, expressed in Sf9 cells

PLK1, PLK, STPK13
ProQinase™ PLK3 0437-0000-1
Yes
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human, full length, GST-HIS fusion protein, expressed in Sf9 cells

PLK3, CNK, FNK, PRK
ProQinase™ PRK1 0207-0000-1
Yes
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human, full length, GST-HIS fusion protein, expressed in Sf9 cells

PKN1, DBK, PKN, PAK1, PRK1, PRKCL1, MGC46204
ProQinase™ PYK2 0363-0000-1
No
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human, full length, GST-HIS fusion protein, expressed in Sf9 cells

PTK2B, CADTK, CAKB, FADK2, FAK2, PKB, PTK, PYK2, RAFTK, CAK beta
ProQinase™ RAF1 YDYD 0792-0000-2
Yes
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human, C-terminal fragment, mutationally activated (Y340D; Y341D), untagged, expressed in Sf9 cells

RAF1, c-RAF, RAF1 Y340D/Y341D (untagged)
ProQinase™ RAF1 YDYD (GST-HIS-tag) 0792-0000-1
No
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human, C-terminal fragment, mutationally activated (Y340D, Y341D), GST-HIS fusion protein, expressed in Sf9 cells

RAF1, c-RAF, RAF1 Y340D/Y341D (GST-HIS-tag)
ProQinase™ RET 1090-0000-1
Yes
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human, C-terminal fragment, GST-HIS fusion protein, expressed in Sf9 cells

RET, CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51, RET-ELE1, RET wt
ProQinase™ RET E762Q 1093-0000-1
Yes
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human, C-terminal fragment, E762Q mutation, GST-HIS fusion protein, expressed in Sf9 cells

RET, CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51, RET-ELE1
ProQinase™ RET G691S 1091-0000-1
Yes
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human, C-terminal fragment, G691S mutation, GST-HIS fusion protein, expressed in Sf9 cells

RET, CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51, RET-ELE1
ProQinase™ RET G810C 1725-0000-1
Yes
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human, C-terminal fragment, G810C mutation, GST-HIS fusion protein, expressed in Sf9 cells

RET, CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51, RET-ELE1
ProQinase™ RET G810R 1724-0000-1
Yes
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human, C-terminal fragment, G810R mutation, GST-HIS fusion protein, expressed in Sf9 cells

RET, CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51, RET-ELE1
ProQinase™ RET G810S 1726-0000-1
Yes
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human, C-terminal fragment, G810S mutation, GST-HIS fusion protein, expressed in Sf9 cells

RET, CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51, RET-ELE1
ProQinase™ RET L730I 1735-0000-1
Yes
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human, C-terminal fragment, L730I mutation, GST-HIS fusion protein, expressed in Sf9 cells

RET, CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51, RET-ELE1, RET wt
ProQinase™ RET L730M 1736-0000-1
Yes
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human, C-terminal fragment, L730M mutation, GST-HIS fusion protein, expressed in Sf9 cells

RET, CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51, RET-ELE1
ProQinase™ RET M918T 1099-0000-1
Yes
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human, C-terminal fragment, M918T mutation, GST-HIS fusion protein, expressed in Sf9 cells

RET, CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51, RET-ELE1
ProQinase™ RET R749T 1092-0000-1
Yes
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human, C-terminal fragment, R749T mutation, GST-HIS fusion protein, expressed in Sf9 cells

RET, CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51, RET-ELE1
ProQinase™ RET R813Q 1097-0000-1
Yes
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human, C-terminal fragment, R813Q mutation, GST-HIS fusion protein, expressed in Sf9 cells

RET, CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51, RET-ELE1
ProQinase™ RET S891A 1098-0000-1
Yes
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human, C-terminal fragment, S891A mutation, GST-HIS fusion protein, expressed in Sf9 cells

RET, CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51, RET-ELE1
ProQinase™ RET V804E 1377-0000-1
Yes
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human, C-terminal fragment, Y806H mutation, GST-HIS fusion protein, expressed in Sf9 cells

RET, CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51, RET-ELE1
ProQinase™ RET V804L 1096-0000-1
Yes
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human, C-terminal fragment, V804L mutation, GST-HIS fusion protein, expressed in Sf9 cells

RET, CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51, RET-ELE1
ProQinase™ RET V804M 1095-0000-1
Yes
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human, C-terminal fragment, V804M mutation, GST-HIS fusion protein, expressed in Sf9 cells

RET, CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51, RET-ELE1
ProQinase™ RET Y791F 1094-0000-1
Yes
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human, C-terminal fragment, Y791F mutation, GST-HIS fusion protein, expressed in Sf9 cells

RET, CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51, RET-ELE1
ProQinase™ RET Y806H 1378-0000-1
Yes
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human, C-terminal fragment, Y806H mutation, GST-HIS fusion protein, expressed in Sf9 cells

RET, CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51, RET-ELE1
ProQinase™ RIPK2 0676-0000-1
No
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human, N-terminal fragment, GST-HIS fusion protein, expressed in Sf9 cells

RIPK2, CARD3, CARDIAK, CCK, GIG30, RICK, RIP-2, RIP2
ProQinase™ RIPK4 1518-0000-1
Yes
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human, N-terminal fragment, GST-HIS fusion protein, expressed in Sf9 cells

RIPK4, ANKK2, ANKRD3, DIK, MGC129992, MGC129993, PKK, RIP4
ProQinase™ ROCK2 0347-0000-1
Yes
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human, internal fragment, GST-HIS fusion protein, expressed in Sf9 cells

ROCK2, KIAA0619, ROC2
ProQinase™ RON 0889-0000-1
No
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human, internal fragment, GST-HIS fusion protein, expressed in Sf9 cells

MST1R, CD136, CDw136, PTK8
ProQinase™ S6K 0318-0000-2
No
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human, internal fragment, activated, GST-HIS fusion protein, expressed in Sf9 cells

RPS6KB1, S6K1, STK14A
ProQinase™ SAK 0306-0000-1
No
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human, full length, GST-HIS fusion protein, expressed in Sf9 cells

PLK4, SAK, STK18
ProQinase™ SGK1 0199-0000-2
Yes
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human, full length, activated, GST fusion protein, expressed in Sf9 cells

SGK, n/a
ProQinase™ SGK3 0198-0000-2
Yes
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human, full length, activated, GST fusion protein, expressed in Sf9 cells

SGKL, CISK, SGK2, SGK3
ProQinase™ SIK1 1338-0000-1
Yes
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human, N-terminal fragment, GST-HIS fusion protein, expressed in Sf9 cells

SIK1, MSK, SNF1LK, SIK, SIK-1, SNF1LK
ProQinase™ SIK2 1371-0000-1
Yes
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human, N-terminal fragment, GST-HIS fusion protein, expressed in Sf9 cells

SIK2, QIK, SNF1LK2
ProQinase™ SIK3 1340-0000-1
Yes
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human, N-terminal fragment, GST-HIS fusion protein, expressed in Sf9 cells

SIK3, L19, QSK, SIK-3
ProQinase™ SNARK 0414-0000-1
Yes
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human, full length, GST-HIS fusion protein, expressed in Sf9 cells

NUAK2, DKFZp434J037
ProQinase™ SNK 0277-0000-1
Yes
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human, full length, GST-HIS fusion protein, expressed in Sf9 cells

PLK2, SNK
ProQinase™ SRC 0200-0000-1
Yes
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human, full length, GST-HIS fusion protein, expressed in Sf9 cells

SRC, ASV, SRC1, c-SRC, p60-Src, SRC (GST-HIS-tag)
ProQinase™ SRC (HIS-tag) 0260-0000-1
No
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human, full length, HIS fusion protein, expressed in Sf9 cells

SRC, ASV, SRC1, c-SRC, p60-Src
ProQinase™ SRPK1 0434-0000-1
Yes
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human, full length, GST-HIS fusion protein, expressed in Sf9 cells

SRPK1, SFRSK1
ProQinase™ SRPK2 0381-0000-1
Yes
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human, full length, GST-HIS fusion protein, expressed in Sf9 cells

SRPK2, SFRSK2
ProQinase™ SYK 0244-0000-1
No
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human, full length, GST-HIS fusion protein, expressed in Sf9 cells

SYK, n/a, SYK aa1-635
ProQinase™ SYK aa356-635 0860-0000-1
No
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human, internal fragment, HIS fusion protein, expressed in Sf9 cells

SYK
ProQinase™ TAOK3 0908-0000-1
Yes
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human, full-length, untagged, expressed in Sf9 cells

TAOK3, DPK, JIK, MAP3K18, TAO kinase 3
ProQinase™ TBK1 0749-0000-1
Yes
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human, full-length, untagged, expressed in Sf9 cells

TBK1, CDC37, HSPCA, HSPCB, IKBKG, NAK, T2K, TANK, TRAF2
ProQinase™ TGFBR1 0397-0000-1
Yes
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human, C-terminal fragment, GST-HIS fusion protein, expressed in Sf9 cells

TGFBR1, ALK5, ACVRLK4, TGFB-R1
ProQinase™ TIE2 0861-0000-1
Yes
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human, C-terminal fragment, activated, GST-HIS fusion protein, expressed in Sf9 cells

TEK, VMCM, TIE-2, VMCM1, CD202B, TIE2 wt
ProQinase™ TIE2 R849W 1085-0000-1
Yes
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human, C-terminal fragment, R849W mutation, activated, GST-HIS fusion protein, expressed in Sf9 cells

TEK, VMCM, TIE-2, VMCM1, CD202B
ProQinase™ TIE2 Y1108F 1088-0000-1
Yes
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human, C-terminal fragment, Y1108F mutation, activated, GST-HIS fusion protein, expressed in Sf9 cells

TEK, VMCM, TIE-2, VMCM1, CD202B
ProQinase™ TIE2 Y897S 1086-0000-1
Yes
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human, C-terminal fragment, Y897S mutation, activated, GST-HIS fusion protein, expressed in Sf9 cells

TEK, VMCM, TIE-2, VMCM1, CD202B
ProQinase™ TLK1 1109-0000-1
Yes
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human, C-terminal fragment, N-terminal FLAG, C-terminal HIS8-tagged fusion protein, expressed in Sf9 cells

TLK1, PKU-beta, KIAA0137
ProQinase™ TLK2 1110-0000-1
Yes
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human, C-terminal fragment, N-terminal FLAG, C-terminal HIS8-tagged fusion protein, expressed in Sf9 cells

TLK2, MGC44450, PKU-ALPHA
ProQinase™ TNK1 1413-0000-1
Yes
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human, internal fragment, GST-HIS fusion protein, expressed in Sf9 cells

TNK1, n/a
ProQinase™ TRKA 0311-0000-2
Yes
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human, C-terminal fragment, activated, GST-HIS fusion protein, expressed in Sf9 cells

NTRK1, MTC, TRK, TRK1, TRKA, TRK-A wt
ProQinase™ TRKA G667C 1537-0000-1
Yes
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human, C-terminal fragment, activated, GST-HIS fusion protein, expressed in Sf9 cells

MTC, TRK1, TRKA, TRK-A G667C
ProQinase™ TRKB 0686-0000-1
Yes
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human, C-terminal fragment, activated, GST-HIS fusion protein, expressed in Sf9 cells

NTRK2, GP145-TrkB, TRKB, Trk-B, TRK-B
ProQinase™ TRKC 0775-0000-1
Yes
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human, C-terminal fragment, activated, GST-HIS fusion protein, expressed in Sf9 cells

NTRK3, GP145-TrkC, TRKC, Trk-C, TRK-C
ProQinase™ TSF1 0187-0000-1
No
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human, full length, GST-HIS fusion protein, expressed in Sf9 cells

STK16, KRCT, MPSK, PKL12
ProQinase™ TSK2 0220-0000-1
Yes
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human, full length, GST-HIS fusion protein, expressed in Sf9 cells

TSSK2, DGS-G, SPOGA2, FLJ38613
ProQinase™ TTBK1 1358-0000-1
No
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human, full length, GST-HIS tag, expressed in Sf9 cells

TTBK1, BDTK, TTBK1 aa1-1321
ProQinase™ TTBK1 aa1-480 1731-0000-1
Yes
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human, N-terminal fragment, GST-HIS fusion protein, expressed in Sf9 cells

TTBK1, BDTK
ProQinase™ TTBK2 1359-0000-1
Yes
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human, full length, GST-HIS fusion protein, expressed in Sf9 cells

TTBK2, BDTK, KIAA1855, RP3-330M21.4
ProQinase™ TTK 0284-0000-1
No
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human, full length,GST-HIS fusion protein, expressed in Sf9 cells

TTK, ESK, MPS1L1, PYT
ProQinase™ TYRO3 0449-0000-1
Yes
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human, C-terminal fragment, GST-HIS fusion protein, expressed in Sf9 cells

TYRO3, BYK, Brt, Dtk, Sky, Tif
ProQinase™ ULK2 1670-0000-1
No
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human, N-terminal fragment, GST-HIS fusion protein, expressed in Sf9 cells

ULK2, ATG1B, KIAA0623, Unc51.2
ProQinase™ VEGFR1 0097-0000-3
Yes
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human, C-terminal fragment, activated, GST-HIS fusion protein, expressed in Sf9 cells

FLT1, FLT, VEGF-R1
ProQinase™ VEGFR2 0096-0000-1
Yes
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human, C-terminal fragment, GST fusion protein, expressed in Sf9 cells

KDR, FLK1, VEGFR, VEGF-R2
ProQinase™ VEGFR3 0225-0000-2
Yes
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human, C-terminal fragment, activated, GST-HIS fusion protein, expressed in Sf9 cells

FLT4, PCL, VEGF-R3
ProQinase™ VRK1 0302-0000-1
Yes
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human, full length, GST-HIS fusion protein, expressed in Sf9 cells

VRK1, n/a
ProQinase™ VRK2 1520-0000-1
No
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human, N-terminal fragment, GST-HIS fusion protein, expressed in Sf9 cells

VRK2, n/a
ProQinase™ WEE1 0136-0000-1
No
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human, C-terminal fragment, GST-HIS fusion protein, expressed in Sf9 cells

WEE1, WEE1hu
ProQinase™ WNK1 1111-0000-1
Yes
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human, internal fragment, N-terminal FLAG, C-terminal HIS8-tagged fusion protein, expressed in Sf9 cells

WNK1, KDP, KIAA0344, PHA2C, PRKWNK1
ProQinase™ YES 0362-0000-1
Yes
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human, full length, GST-HIS fusion protein, expressed in Sf9 cells

YES, C-YES, HsT441, P61-YES
ProQinase™ ZAP70 0364-0000-1
Yes
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human, full length, GST-HIS fusion protein, expressed in Sf9 cells

ZAP70, SRK, STD, TZK, ZAP-70
EXCEL

Info in Brief

Host of Expression

Sf9 insect cells, E.coli

Tag of Kinase

GST-HIS, GST, HIS, Untagged

Item Size

10 μg, 100 μg, 1 mg, bulk

Purification & Activation

Affinity chromatography Activation by upstream kinase, ATPauto-activation, or co-expression with activating partner, if required

Quality Control

Determination of purity & identity (Coomassie, LC-ESI-MS/MS mass spectrometry) Validation of kinase activity (Vmax/ATP-Km) FlashPlate™-based radiometric assay

Assay Technologies at ProQinase

All active protein kinases are successfully checked for application in radiometric filter binding assays & FlashPlate™-based assays. In addition, for most kinases the application in the ADP-Glo™ kinase assay (Promega) has been demonstrated (see table above).

Global Delivery

Within 2 days after the receipt of a purchase order
US customers are served from our US storage site

Prospective

More protein kinases are under development

Material Safety Data Sheet

PDF